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The Relationship between Telomere Length and Nucleoplasmic Bridges and Severity of Disease in Prostate Cancer Patients

SIMPLE SUMMARY: Telomeres are essential to prevent telomere end fusions that cause the formation of dicentric chromosomes and nucleoplasmic bridges (NPBs) which in turn induce chromosomal instability, cancer initiation and progression. In this study, we show that telomere length (TL) is reduced and...

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Detalles Bibliográficos
Autores principales: Dhillon, Varinderpal S., Deo, Permal, Fenech, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340763/
https://www.ncbi.nlm.nih.gov/pubmed/37444460
http://dx.doi.org/10.3390/cancers15133351