The Hippo Pathway Effectors YAP/TAZ-TEAD Oncoproteins as Emerging Therapeutic Targets in the Tumor Microenvironment

SIMPLE SUMMARY: YAP/TAZ are the central effectors of the Hippo pathway and orchestrate their oncogenic program by binding to TEAD transcriptional factors. Here, we document a comprehensive understanding of how YAP/TAZ dependent tumors could be exploited for improving cancer therapies. Aside from pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Mokhtari, Reza Bayat, Ashayeri, Neda, Baghaie, Leili, Sambi, Manpreet, Satari, Kosar, Baluch, Narges, Bosykh, Dmitriy A., Szewczuk, Myron R., Chakraborty, Sayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340833/
https://www.ncbi.nlm.nih.gov/pubmed/37444578
http://dx.doi.org/10.3390/cancers15133468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340833/
https://www.ncbi.nlm.nih.gov/pubmed/37444578
http://dx.doi.org/10.3390/cancers15133468

Ejemplares similares