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The Hippo Pathway Effectors YAP/TAZ-TEAD Oncoproteins as Emerging Therapeutic Targets in the Tumor Microenvironment

SIMPLE SUMMARY: YAP/TAZ are the central effectors of the Hippo pathway and orchestrate their oncogenic program by binding to TEAD transcriptional factors. Here, we document a comprehensive understanding of how YAP/TAZ dependent tumors could be exploited for improving cancer therapies. Aside from pro...

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Detalles Bibliográficos
Autores principales:	Mokhtari, Reza Bayat, Ashayeri, Neda, Baghaie, Leili, Sambi, Manpreet, Satari, Kosar, Baluch, Narges, Bosykh, Dmitriy A., Szewczuk, Myron R., Chakraborty, Sayan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340833/ https://www.ncbi.nlm.nih.gov/pubmed/37444578 http://dx.doi.org/10.3390/cancers15133468

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