Allele-Specific Epigenetic Regulation of FURIN Expression at a Coronary Artery Disease Susceptibility Locus

Genome-wide association studies have revealed an association between the genetic variant rs17514846 in the FURIN gene and coronary artery disease. We investigated the mechanism through which rs17514846 modulates FURIN expression. An analysis of isogenic monocytic cell lines showed that the cells of...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Cao, Junjun, McVey, David G., Ye, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341058/
https://www.ncbi.nlm.nih.gov/pubmed/37443715
http://dx.doi.org/10.3390/cells12131681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341058/
https://www.ncbi.nlm.nih.gov/pubmed/37443715
http://dx.doi.org/10.3390/cells12131681

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