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Efficacy of a HER2-Targeted Thorium-227 Conjugate in a HER2-Positive Breast Cancer Bone Metastasis Model

SIMPLE SUMMARY: Human epidermal growth factor receptor 2 (HER2) is a protein present in increased amounts in breast cancer compared with healthy breast tissue. Anti-cancer drugs directed at HER2 can therefore kill cancer cells while reducing harmful effects to adjacent normal cells that do not have...

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Detalles Bibliográficos
Autores principales: Karlsson, Jenny, Hagemann, Urs B., Cruciani, Véronique, Schatz, Christoph A., Grant, Derek, Ellingsen, Christine, Kristian, Alexander, Katoozi, Shirin, Mihaylova, Dessislava, Uran, Steinar R., Suominen, Mari, Bjerke, Roger M., Ryan, Olav B., Cuthbertson, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341074/
https://www.ncbi.nlm.nih.gov/pubmed/37444529
http://dx.doi.org/10.3390/cancers15133419