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Actin Cytoskeleton Polymerization and Focal Adhesion as Important Factors in the Pathomechanism and Potential Targets of Mucopolysaccharidosis Treatment

The main approach used in the current therapy of mucopolysaccharidosis (MPS) is to reduce the levels of glycosaminoglycans (GAGs) in cells, the deposits considered to be the main cause of the disease. Previous studies have revealed significant differences in the expression of genes encoding proteins...

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Detalles Bibliográficos
Autores principales: Gaffke, Lidia, Rintz, Estera, Pierzynowska, Karolina, Węgrzyn, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341097/
https://www.ncbi.nlm.nih.gov/pubmed/37443816
http://dx.doi.org/10.3390/cells12131782