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Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9

SIMPLE SUMMARY: In cancer patients, immunotherapy using targeted antibodies is often not effective in the long term due to resistance mechanisms developed by cancer cells. Tumors often overexpress certain molecules on the cell surface, that bind to specific receptors on immune cells, such as myeloid...

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Detalles Bibliográficos
Autores principales: Chan, Chilam, Lustig, Marta, Jansen, J. H. Marco, Garcia Villagrasa, Laura, Raymakers, Leon, Daamen, Lois A., Valerius, Thomas, van Tetering, Geert, Leusen, Jeanette H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341145/
https://www.ncbi.nlm.nih.gov/pubmed/37444515
http://dx.doi.org/10.3390/cancers15133405