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SHARPIN Enhances Ferroptosis in Synovial Sarcoma Cells via NF-κB- and PRMT5-Mediated PGC1α Reduction

SIMPLE SUMMARY: Sarcoma is difficult to treat because of its rarity. Ferroptosis is a new type of cell death mediated by ferrous iron. In the present study, we aimed to clarify the effect of ferroptosis in sarcoma. As compared with noncancer and carcinoma cell lines, ferroptosis is more sensitive in...

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Detalles Bibliográficos
Autores principales: Tamiya, Hironari, Urushihara, Naoko, Shizuma, Kazuko, Ogawa, Hisataka, Nakai, Sho, Wakamatsu, Toru, Takenaka, Satoshi, Kakunaga, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341212/
https://www.ncbi.nlm.nih.gov/pubmed/37444594
http://dx.doi.org/10.3390/cancers15133484