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Development of Woolly Hair and Hairlessness in a CRISPR−Engineered Mutant Mouse Model with KRT71 Mutations

Hypotrichosis simplex (HS) and woolly hair (WH) are rare and monogenic disorders of hair loss. HS, characterized by a diffuse loss of hair, usually begins in early childhood and progresses into adulthood. WH displays strong coiled hair involving a localized area of the scalp or covering the entire s...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Yao, Hongwu, Wang, Hejun, Sui, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341341/
https://www.ncbi.nlm.nih.gov/pubmed/37443815
http://dx.doi.org/10.3390/cells12131781