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Antibodies Capable of Enhancing SARS-CoV-2 Infection Can Circulate in Patients with Severe COVID-19

Antibody-dependent enhancement (ADE) has been shown previously for SARS-CoV-1, MERS-CoV, and SARS-CoV-2 infection in vitro. In this study, the first monoclonal antibody (mAb) that causes ADE in a SARS-CoV-2 in vivo model was identified. mAb RS2 against the SARS-CoV-2 S-protein was developed using hy...

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Detalles Bibliográficos
Autores principales: Matveev, Andrey, Pyankov, Oleg, Khlusevich, Yana, Tyazhelkova, Olga, Emelyanova, Lyudmila, Timofeeva, Anna, Shipovalov, Andrey, Chechushkov, Anton, Zaitseva, Natalia, Kudrov, Gleb, Yusubalieva, Gaukhar, Yussubaliyeva, Saule, Zhukova, Oxana, Baklaushev, Vladimir, Sedykh, Sergey, Lifshits, Galina, Tikunov, Artem, Tikunova, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341398/
https://www.ncbi.nlm.nih.gov/pubmed/37445984
http://dx.doi.org/10.3390/ijms241310799