Cross-Linking Mass Spectrometry on P-Glycoprotein

The ABC transporter P-glycoprotein (Pgp) has been found to be involved in multidrug resistance in tumor cells. Lipids and cholesterol have a pivotal role in Pgp’s conformations; however, it is often difficult to investigate it with conventional structural biology techniques. Here, we applied robust...

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Detalles Bibliográficos
Autores principales: Gellen, Gabriella, Klement, Eva, Biwott, Kipchumba, Schlosser, Gitta, Kalló, Gergő, Csősz, Éva, Medzihradszky, Katalin F., Bacso, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341432/
https://www.ncbi.nlm.nih.gov/pubmed/37445813
http://dx.doi.org/10.3390/ijms241310627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341432/
https://www.ncbi.nlm.nih.gov/pubmed/37445813
http://dx.doi.org/10.3390/ijms241310627

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