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Cross-Linking Mass Spectrometry on P-Glycoprotein
The ABC transporter P-glycoprotein (Pgp) has been found to be involved in multidrug resistance in tumor cells. Lipids and cholesterol have a pivotal role in Pgp’s conformations; however, it is often difficult to investigate it with conventional structural biology techniques. Here, we applied robust...
Autores principales: | Gellen, Gabriella, Klement, Eva, Biwott, Kipchumba, Schlosser, Gitta, Kalló, Gergő, Csősz, Éva, Medzihradszky, Katalin F., Bacso, Zsolt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341432/ https://www.ncbi.nlm.nih.gov/pubmed/37445813 http://dx.doi.org/10.3390/ijms241310627 |
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