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Microcystin-LR-Induced Interaction between M2 Tumor-Associated Macrophage and Colorectal Cancer Cell Promotes Colorectal Cancer Cell Migration through Regulating the Expression of TGF-β1 and CST3

Microcystin-LR (MC-LR) is a toxic secondary metabolite produced by cyanobacteria that has been demonstrated to promote colorectal cancer (CRC). However, the mechanism by which MC-LR enhances CRC in the tumor microenvironment (TME) is poorly understood. To elucidate its role in TME, a co-culture syst...

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Detalles Bibliográficos
Autores principales: Jiang, Xinying, Zhang, Hailing, Zhang, Hengshuo, Wang, Fan, Wang, Xiaochang, Ding, Tong, Zhang, Xuxiang, Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341441/
https://www.ncbi.nlm.nih.gov/pubmed/37445705
http://dx.doi.org/10.3390/ijms241310527