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Potentiation of Cisplatin Cytotoxicity in Resistant Ovarian Cancer SKOV3/Cisplatin Cells by Quercetin Pre-Treatment

Previously, we demonstrated that the overexpression of antioxidant enzymes (SOD-1, SOD-2, Gpx-1, CAT, and HO-1), transcription factor NFE2L2, and the signaling pathway (PI3K/Akt/mTOR) contribute to the cisplatin resistance of SKOV-3/CDDP ovarian cells, and treatment with quercetin (QU) alone has bee...

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Detalles Bibliográficos
Autores principales: Hasan, Aseel Ali, Kalinina, Elena, Nuzhina, Julia, Volodina, Yulia, Shtil, Alexander, Tatarskiy, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341453/
https://www.ncbi.nlm.nih.gov/pubmed/37446140
http://dx.doi.org/10.3390/ijms241310960