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Structurally and Morphologically Distinct Pathological Tau Assemblies Differentially Affect GVB Accumulation
Tau aggregation is central to the pathogenesis of a large group of neurodegenerative diseases termed tauopathies, but it is still unclear in which way neurons respond to tau pathology and how tau accumulation leads to neurodegeneration. A striking neuron-specific response to tau pathology is present...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341458/ https://www.ncbi.nlm.nih.gov/pubmed/37446051 http://dx.doi.org/10.3390/ijms241310865 |