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Structurally and Morphologically Distinct Pathological Tau Assemblies Differentially Affect GVB Accumulation

Tau aggregation is central to the pathogenesis of a large group of neurodegenerative diseases termed tauopathies, but it is still unclear in which way neurons respond to tau pathology and how tau accumulation leads to neurodegeneration. A striking neuron-specific response to tau pathology is present...

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Detalles Bibliográficos
Autores principales: Jorge-Oliva, Marta, van Weering, Jan R. T., Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341458/
https://www.ncbi.nlm.nih.gov/pubmed/37446051
http://dx.doi.org/10.3390/ijms241310865