Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome

Immunoproteasome inhibition is a promising strategy for the treatment of hematological malignancies, autoimmune diseases, and inflammatory diseases. The design of non-covalent inhibitors of the immunoproteasome β1i/β5i catalytic subunits could be a novel approach to avoid the drawbacks of the known...

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Detalles Bibliográficos
Autores principales: Culletta, Giulia, Tutone, Marco, Ettari, Roberta, Perricone, Ugo, Di Chio, Carla, Almerico, Anna Maria, Zappalà, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341482/
https://www.ncbi.nlm.nih.gov/pubmed/37445688
http://dx.doi.org/10.3390/ijms241310504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341482/
https://www.ncbi.nlm.nih.gov/pubmed/37445688
http://dx.doi.org/10.3390/ijms241310504

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