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EZH2 Gene Knockdown Inhibits Sheep Pituitary Cell Proliferation via Downregulating the AKT/ERK Signaling Pathway

Pituitary gonadotropins perform essential functions in mammalian reproduction by stimulating gametogenesis and steroidogenesis in the ovaries and testicles. EZH2 is a histone methyltransferase that inhibits proliferation and aggravates apoptosis in stem cells subjected to pathological stimuli. Howev...

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Detalles Bibliográficos
Autores principales: Cai, Yu, Chen, Peiyong, Xu, Hui, Li, Shanglai, Zhao, Bingru, Fan, Yixuan, Wang, Feng, Zhang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341494/
https://www.ncbi.nlm.nih.gov/pubmed/37445833
http://dx.doi.org/10.3390/ijms241310656