Cargando…

Metabolic Fingerprints of Effective Fluoxetine Treatment in the Prefrontal Cortex of Chronically Socially Isolated Rats: Marker Candidates and Predictive Metabolites

The increasing prevalence of depression requires more effective therapy and the understanding of antidepressants’ mode of action. We carried out untargeted metabolomics of the prefrontal cortex of rats exposed to chronic social isolation (CSIS), a rat model of depression, and/or fluoxetine treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Filipović, Dragana, Inderhees, Julica, Korda, Alexandra, Tadić, Predrag, Schwaninger, Markus, Inta, Dragoš, Borgwardt, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341512/
https://www.ncbi.nlm.nih.gov/pubmed/37446133
http://dx.doi.org/10.3390/ijms241310957