Rapid Generation and Molecular Docking Analysis of Single-Chain Fragment Variable (scFv) Antibody Selected by Ribosome Display Targeting Cholecystokinin B Receptor (CCK-BR) for Reduction of Chronic Neuropathic Pain

A robust cell-free platform technology, ribosome display in combination with cloning, expression, and purification was utilized to develop single chain Fragment variable (scFv) antibody variants as pain therapy directed at the mouse cholecystokinin B (CCK-B) receptor. Three effective CCK-B peptide-s...

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Detalles Bibliográficos
Autores principales: Kunamneni, Adinarayana, Montera, Marena A., Durvasula, Ravi, Alles, Sascha R. A., Goyal, Sachin, Westlund, Karin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341521/
https://www.ncbi.nlm.nih.gov/pubmed/37446213
http://dx.doi.org/10.3390/ijms241311035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341521/
https://www.ncbi.nlm.nih.gov/pubmed/37446213
http://dx.doi.org/10.3390/ijms241311035

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