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Synonymous Variants of Uncertain Silence

Synonymous variants, traditionally regarded as silent mutations due to their lack of impact on protein sequence, structure and function, have been the subject of increasing scrutiny. This commentary explores the emerging evidence challenging the notion of synonymous variants as functionally inert. A...

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Detalles Bibliográficos
Autores principales: Giacoletto, Christopher J., Rotter, Jerome I., Grody, Wayne W., Schiller, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341574/
https://www.ncbi.nlm.nih.gov/pubmed/37445732
http://dx.doi.org/10.3390/ijms241310556