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Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait

Sickle cell disease (SCD) is caused by the homozygous beta-globin gene mutation that can lead to ischemic multi-organ damage and consequently reduce life expectancy. On the other hand, sickle cell trait (SCT), the heterozygous beta-globin gene mutation, is still considered a benign condition. Althou...

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Detalles Bibliográficos
Autores principales: Trucas, Marcello, Burattini, Sabrina, Porcu, Susanna, Simbula, Michela, Ristaldi, Maria Serafina, Kowalik, Marta Anna, Serra, Maria Pina, Gobbi, Pietro, Battistelli, Michela, Perra, Andrea, Quartu, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341605/
https://www.ncbi.nlm.nih.gov/pubmed/37445630
http://dx.doi.org/10.3390/ijms241310452