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RNA Sequencing Reveals Unique Transcriptomic Signatures of the Thyroid in a Murine Lung Cancer Model Treated with PD-1 and PD-L1 Antibodies

Immune checkpoint inhibitors (ICI) are commonly associated with thyroid immune-related adverse events, yet the mechanism has not been fully elucidated. We aimed to further explore the mechanism of ICI-induced thyroid dysfunction by assessing changes induced in the thyroid transcriptome by ICI treatm...

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Detalles Bibliográficos
Autores principales: Pollack, Rena, Stokar, Joshua, Lishinsky, Natan, Gurt, Irina, Kaisar-Iluz, Naomi, Shaul, Merav E., Fridlender, Zvi G., Dresner-Pollak, Rivka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341615/
https://www.ncbi.nlm.nih.gov/pubmed/37445704
http://dx.doi.org/10.3390/ijms241310526