Improving Soluble Expression of SARS-CoV-2 Spike Priming Protease TMPRSS2 with an Artificial Fusing Protein

SARS-CoV-2 relies on the recognition of the spike protein by the host cell receptor ACE2 for cellular entry. In this process, transmembrane serine protease 2 (TMPRSS2) plays a pivotal role, as it acts as the principal priming agent catalyzing spike protein cleavage to initiate the fusion of the cell...

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Detalles Bibliográficos
Autores principales: Ye, Xiao, Ling, Xue, Wu, Min, Bai, Guijie, Yuan, Meng, Rao, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341623/
https://www.ncbi.nlm.nih.gov/pubmed/37445653
http://dx.doi.org/10.3390/ijms241310475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341623/
https://www.ncbi.nlm.nih.gov/pubmed/37445653
http://dx.doi.org/10.3390/ijms241310475

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