Repurposing Simvastatin in Parkinson’s Disease Model: Protection Is throughout Modulation of the Neuro-Inflammatory Response in the Substantia nigra

Parkinson’s disease is a neurodegenerative disorder characterized by oxidative stress and immune activation in the nigro-striatal pathway. Simvastatin regulates cholesterol metabolism and protects from atherosclerosis disease. Simvastatin-tween 80 was administered 7 days before sterotaxic intrastria...

Descripción completa

Detalles Bibliográficos
Autores principales: Rubio-Osornio, Moisés, León, Carmen T. Goméz-De, Montes, Sergio, Rubio, Carmen, Ríos, Camilo, Monroy, Antonio, Morales-Montor, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341642/
https://www.ncbi.nlm.nih.gov/pubmed/37445592
http://dx.doi.org/10.3390/ijms241310414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341642/
https://www.ncbi.nlm.nih.gov/pubmed/37445592
http://dx.doi.org/10.3390/ijms241310414

Ejemplares similares