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Repurposing Simvastatin in Parkinson’s Disease Model: Protection Is throughout Modulation of the Neuro-Inflammatory Response in the Substantia nigra
Parkinson’s disease is a neurodegenerative disorder characterized by oxidative stress and immune activation in the nigro-striatal pathway. Simvastatin regulates cholesterol metabolism and protects from atherosclerosis disease. Simvastatin-tween 80 was administered 7 days before sterotaxic intrastria...
Autores principales: | Rubio-Osornio, Moisés, León, Carmen T. Goméz-De, Montes, Sergio, Rubio, Carmen, Ríos, Camilo, Monroy, Antonio, Morales-Montor, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341642/ https://www.ncbi.nlm.nih.gov/pubmed/37445592 http://dx.doi.org/10.3390/ijms241310414 |
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