Spermidine Attenuates High Glucose-Induced Oxidative Damage in Retinal Pigment Epithelial Cells by Inhibiting Production of ROS and NF-κB/NLRP3 Inflammasome Pathway

Diabetic retinopathy (DR) is the leading cause of vision loss and a critical complication of diabetes with a very complex etiology. The build-up of reactive oxygen species (ROS) due to hyperglycemia is recognized as a primary risk factor for DR. Although spermidine, a naturally occurring polyamine,...

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Detalles Bibliográficos
Autores principales: Bang, EunJin, Park, Cheol, Hwangbo, Hyun, Shim, Jung-Hyun, Leem, Sun-Hee, Hyun, Jin Won, Kim, Gi-Young, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341649/
https://www.ncbi.nlm.nih.gov/pubmed/37445726
http://dx.doi.org/10.3390/ijms241310550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341649/
https://www.ncbi.nlm.nih.gov/pubmed/37445726
http://dx.doi.org/10.3390/ijms241310550

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