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Pharmacogenetic Guided Opioid Therapy Improves Chronic Pain Outcomes and Comorbid Mental Health: A Randomized, Double-Blind, Controlled Study

Interindividual variability in analgesic response is at least partly due to well-characterized polymorphisms that are associated with opioid dosing and adverse outcomes. The Clinical Pharmacogenetics Implementation Consortium (CPIC) has put forward recommendations for the CYP2D6 phenotype, but the l...

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Detalles Bibliográficos
Autores principales: Agulló, Laura, Aguado, Isidro, Muriel, Javier, Margarit, César, Gómez, Alba, Escorial, Mónica, Sánchez, Astrid, Fernández, Alicia, Peiró, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341655/
https://www.ncbi.nlm.nih.gov/pubmed/37445931
http://dx.doi.org/10.3390/ijms241310754