In Silico Screening and Anticancer-Apoptotic Evaluation of Newly Synthesized Thienopyrimidine/Sulfonamide Hybrids

This work describes the design and synthesis of new hybrids of thienopyrimidine and sulfonamides. The binding affinity of the prepared compounds to FGFR-1 enzyme and caspase-3 was investigated via molecular docking. The cytotoxic effect was estimated for the synthesized compounds against human breas...

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Detalles Bibliográficos
Autores principales: Elmongy, Elshaymaa I., Binjubair, Faizah A., Alshehri, Ohoud Y., Baeshen, Kholoud A., Almukhalfi, Zaha A., Henidi, Hanan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341658/
https://www.ncbi.nlm.nih.gov/pubmed/37446005
http://dx.doi.org/10.3390/ijms241310827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341658/
https://www.ncbi.nlm.nih.gov/pubmed/37446005
http://dx.doi.org/10.3390/ijms241310827

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