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Mitochondria-Targeted Delivery Strategy of Dual-Loaded Liposomes for Alzheimer’s Disease Therapy

Liposomes modified with tetradecyltriphenylphosphonium bromide with dual loading of α-tocopherol and donepezil hydrochloride were successfully designed for intranasal administration. Physicochemical characteristics of cationic liposomes such as the hydrodynamic diameter, zeta potential, and polydisp...

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Detalles Bibliográficos
Autores principales: Vasileva, Leysan, Gaynanova, Gulnara, Valeeva, Farida, Belyaev, Grigory, Zueva, Irina, Bushmeleva, Kseniya, Sibgatullina, Guzel, Samigullin, Dmitry, Vyshtakalyuk, Alexandra, Petrov, Konstantin, Zakharova, Lucia, Sinyashin, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341710/
https://www.ncbi.nlm.nih.gov/pubmed/37445673
http://dx.doi.org/10.3390/ijms241310494