Cargando…

Mitochondria-Targeted Delivery Strategy of Dual-Loaded Liposomes for Alzheimer’s Disease Therapy

Liposomes modified with tetradecyltriphenylphosphonium bromide with dual loading of α-tocopherol and donepezil hydrochloride were successfully designed for intranasal administration. Physicochemical characteristics of cationic liposomes such as the hydrodynamic diameter, zeta potential, and polydisp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vasileva, Leysan, Gaynanova, Gulnara, Valeeva, Farida, Belyaev, Grigory, Zueva, Irina, Bushmeleva, Kseniya, Sibgatullina, Guzel, Samigullin, Dmitry, Vyshtakalyuk, Alexandra, Petrov, Konstantin, Zakharova, Lucia, Sinyashin, Oleg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341710/ https://www.ncbi.nlm.nih.gov/pubmed/37445673 http://dx.doi.org/10.3390/ijms241310494

Ejemplares similares

Mitochondria-Targeted Lipid Nanoparticles Loaded with Rotenone as a New Approach for the Treatment of Oncological Diseases
por: Vasileva, Leysan, et al.
Publicado: (2023)

Supramolecular Tools to Improve Wound Healing and Antioxidant Properties of Abietic Acid: Biocompatible Microemulsions and Emulgels
por: Mirgorodskaya, Alla, et al.
Publicado: (2022)

Synthesis, Properties, and Biomedical Application of Dicationic Gemini Surfactants with Dodecane Spacer and Carbamate Fragments
por: Vasileva, Leysan, et al.
Publicado: (2023)

Self-Assembling Drug Formulations with Tunable Permeability and Biodegradability
por: Gaynanova, Gulnara, et al.
Publicado: (2021)

Transdermal Delivery of 2-PAM as a Tool to Increase the Effectiveness of Traditional Treatment of Organophosphate Poisoning
por: Vasileva, Leysan, et al.
Publicado: (2022)

Self-Assembly of Amphiphilic Compounds as a Versatile Tool for Construction of Nanoscale Drug Carriers
por: Kashapov, Ruslan, et al.
Publicado: (2020)

Manipulation of New Fluorescent Magnetic Nanoparticles with an Electromagnetic Needle, Allowed Determining the Viscosity of the Cytoplasm of M-HeLa Cells
por: Ramazanova, Iliza, et al.
Publicado: (2023)

Oxime Therapy for Brain AChE Reactivation and Neuroprotection after Organophosphate Poisoning
por: Kuznetsova, Darya A., et al.
Publicado: (2022)

Can Activation of Acetylcholinesterase by β-Amyloid Peptide Decrease the Effectiveness of Cholinesterase Inhibitors?
por: Zueva, Irina V., et al.
Publicado: (2023)

Antioxidative and Immunomodulating Properties of Aronia melanocarpa Extract Rich in Anthocyanins
por: Bushmeleva, Kseniya, et al.
Publicado: (2022)

Aronia melanocarpa Flavonol Extract—Antiradical and Immunomodulating Activities Analysis
por: Bushmeleva, Kseniya, et al.
Publicado: (2023)

The Formation of Morphologically Stable Lipid Nanocarriers for Glioma Therapy
por: Pavlov, Rais, et al.
Publicado: (2023)

Enhancement of the Transdermal Delivery of Nonsteroidal Anti-inflammatory Drugs Using Liposomes Containing Cationic Surfactants
por: Kuznetsova, Darya A., et al.
Publicado: (2022)

Radical Scavenging Actions and Immunomodulatory Activity of Aronia melanocarpa Propylene Glycol Extracts
por: Bushmeleva, Kseniya, et al.
Publicado: (2021)

pH-Driven Intracellular Nano-to-Molecular Disassembly of Heterometallic [Au(2)L(2)]{Re(6)Q(8)} Colloids (L = PNNP Ligand; Q = S(2−) or Se(2−))
por: Faizullin, Bulat, et al.
Publicado: (2022)

Comparative Assessment of the Phytochemical Composition and Biological Activity of Extracts of Flowering Plants of Centaurea cyanus L., Centaurea jacea L. and Centaurea scabiosa L.
por: Sharonova, Natalia, et al.
Publicado: (2021)

Therapy of Organophosphate Poisoning via Intranasal Administration of 2-PAM-Loaded Chitosomes
por: Vasilieva, Elmira A., et al.
Publicado: (2022)

Complexation of Oligo- and Polynucleotides with Methoxyphenyl-Functionalized Imidazolium Surfactants
por: Kuznetsova, Darya A., et al.
Publicado: (2022)

Role of Polyanions and Surfactant Head Group in the Formation of Polymer–Colloid Nanocontainers
por: Vasilieva, Elmira A., et al.
Publicado: (2023)

Comparative Analysis of Chemical Profile and Biological Activity of Juniperus communis L. Berry Extracts
por: Belov, Timur, et al.
Publicado: (2023)

Nanocarriers for Biomedicine: From Lipid Formulations to Inorganic and Hybrid Nanoparticles
por: Kashapov, Ruslan, et al.
Publicado: (2021)

Dynamic Interaction of cBid with Detergents, Liposomes and Mitochondria
por: Bleicken, Stephanie, et al.
Publicado: (2012)

Pharmacodynamics of the Glutamate Receptor Antagonists in the Rat Barrel Cortex
por: Vinokurova, Daria, et al.
Publicado: (2018)

Excitatory actions of GABA in the intact neonatal rodent hippocampus in vitro
por: Valeeva, Guzel, et al.
Publicado: (2013)

The Origin of Adrenal Cortical Mitochondria and Liposomes: a Preliminary Report
por: Belt, W. Duane
Publicado: (1958)

Presynaptic Acetylcholine Receptors Modulate the Time Course of Action Potential-Evoked Acetylcholine Quanta Secretion at Neuromuscular Junctions
por: Bukharaeva, Ellya A., et al.
Publicado: (2022)

Bilateral Synchronization of Hippocampal Early Sharp Waves in Neonatal Rats
por: Valeeva, Guzel, et al.
Publicado: (2019)

Antitumor Effect of Hyperoside Loaded in Charge Reversed and Mitochondria-Targeted Liposomes
por: Feng, Yufei, et al.
Publicado: (2021)

Polymorphism of Glutathione S-transferase Genes and the Risk of Toxic Liver Damage in Petrochemical Workers
por: Valeeva, Elvira Timeryanovna, et al.
Publicado: (2020)

Cell-attached recordings of responses evoked by photorelease of GABA in the immature cortical neurons
por: Minlebaev, Marat, et al.
Publicado: (2013)

Resveratrol-Encapsulated Mitochondria-Targeting Liposome Enhances Mitochondrial Respiratory Capacity in Myocardial Cells
por: Tsujioka, Takao, et al.
Publicado: (2021)

Novel indolin-2-one-substituted methanofullerenes bearing long n-alkyl chains: synthesis and application in bulk-heterojunction solar cells
por: Romanova, Irina P, et al.
Publicado: (2014)

Bone conducted responses in the neonatal rat auditory cortex
por: Makarov, Roman, et al.
Publicado: (2021)

ROS-producing nanomaterial engineered from Cu(I) complexes with P(2)N(2)-ligands for cancer cells treating
por: Faizullin, Bulat A., et al.
Publicado: (2023)

X-ray induced photodynamic therapy (PDT) with a mitochondria-targeted liposome delivery system
por: Gu, Xuefan, et al.
Publicado: (2020)

Activation of Neuronal Nicotinic Receptors Inhibits Acetylcholine Release in the Neuromuscular Junction by Increasing Ca(2+) Flux through Ca(v)1 Channels
por: Zhilyakov, Nikita, et al.
Publicado: (2021)

Novel Mitochondria-Targeted Amphiphilic Aminophosphonium Salts and Lipids Nanoparticles: Synthesis, Antitumor Activity and Toxicity
por: Mironov, Vladimir F., et al.
Publicado: (2023)

The study of acute and chronic toxicity of the sodium-, calcium-, iron-polygalacturonate pharmacological substance in rabbits
por: Minzanova, S.T., et al.
Publicado: (2018)

Transport of Ca(2+) and Ca(2+)-Dependent Permeability Transition in the Liver and Heart Mitochondria of Rats with Different Tolerance to Acute Hypoxia
por: Belosludtsev, Konstantin N., et al.
Publicado: (2020)

Crystal structure of cyclic tris(ferrocene-1,1′-diyl)
por: Shekurov, Ruslan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0fot9jg179bcrg64jm3kglfcpq