Pathophysiology of Cerebellar Degeneration in Mitochondrial Disorders: Insights from the Harlequin Mouse

By means of a proteomic approach, we assessed the pathways involved in cerebellar neurodegeneration in a mouse model (Harlequin, Hq) of mitochondrial disorder. A differential proteomic profile study (iTRAQ) was performed in cerebellum homogenates of male Hq and wild-type (WT) mice 8 weeks after the...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández de la Torre, Miguel, Fiuza-Luces, Carmen, Laine-Menéndez, Sara, Delmiro, Aitor, Arenas, Joaquín, Martín, Miguel Ángel, Lucia, Alejandro, Morán, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341771/
https://www.ncbi.nlm.nih.gov/pubmed/37446148
http://dx.doi.org/10.3390/ijms241310973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341771/
https://www.ncbi.nlm.nih.gov/pubmed/37446148
http://dx.doi.org/10.3390/ijms241310973

Ejemplares similares