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Positive Allosteric Modulator of SERCA Pump NDC-1173 Exerts Beneficial Effects in Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is an irreversible neurodegenerative disease that affects millions of people worldwide. AD does not have a cure and most drug development efforts in the AD field have been focused on targeting the amyloid pathway based on the “amyloid cascade hypothesis”. However, in additio...

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Detalles Bibliográficos
Autores principales: Dahl, Russell, Moore, Amanda C., Knight, Caitlynn, Mauger, Colleen, Zhang, Hua, Schiltz, Gary E., Koss, Wendy A., Bezprozvanny, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341805/
https://www.ncbi.nlm.nih.gov/pubmed/37446234
http://dx.doi.org/10.3390/ijms241311057