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Integrated Clinical, Molecular and Immunological Characterization of Pulmonary Sarcomatoid Carcinomas Reveals an Immune Escape Mechanism That May Influence Therapeutic Strategies

Pulmonary sarcomatoid carcinoma (PSC) has highly aggressive biological behaviour and poor clinical outcomes, raising expectations for new therapeutic strategies. We characterized 179 PSC by immunohistochemistry, next-generation sequencing and in silico analysis using a deep learning algorithm with r...

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Detalles Bibliográficos
Autores principales: Stephan-Falkenau, Susann, Streubel, Anna, Mairinger, Thomas, Blum, Torsten-Gerriet, Kollmeier, Jens, Mairinger, Fabian D., Bauer, Torsten, Pfannschmidt, Joachim, Hollmann, Manuel, Wessolly, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341842/
https://www.ncbi.nlm.nih.gov/pubmed/37445733
http://dx.doi.org/10.3390/ijms241310558