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Quantification of Empty, Partially Filled and Full Adeno-Associated Virus Vectors Using Mass Photometry

Adeno-associated viruses (AAV) are one of the most commonly used vehicles in gene therapies for the treatment of rare diseases. During the AAV manufacturing process, particles with little or no genetic material are co-produced alongside the desired AAV capsid containing the transgene of interest. Be...

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Detalles Bibliográficos
Autores principales: Wagner, Christina, Fuchsberger, Felix F., Innthaler, Bernd, Lemmerer, Martin, Birner-Gruenberger, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341871/
https://www.ncbi.nlm.nih.gov/pubmed/37446211
http://dx.doi.org/10.3390/ijms241311033