Firing of Replication Origins Is Disturbed by a CDK4/6 Inhibitor in a pRb-Independent Manner

Over the last decade, CDK4/6 inhibitors (palbociclib, ribociclib and abemaciclib) have emerged as promising anticancer drugs. Numerous studies have demonstrated that CDK4/6 inhibitors efficiently block the pRb-E2F pathway and induce cell cycle arrest in pRb-proficient cells. Based on these studies,...

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Detalles Bibliográficos
Autores principales: Kim, Su-Jung, Maric, Chrystelle, Briu, Lina-Marie, Fauchereau, Fabien, Baldacci, Giuseppe, Debatisse, Michelle, Koundrioukoff, Stéphane, Cadoret, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341899/
https://www.ncbi.nlm.nih.gov/pubmed/37445805
http://dx.doi.org/10.3390/ijms241310629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341899/
https://www.ncbi.nlm.nih.gov/pubmed/37445805
http://dx.doi.org/10.3390/ijms241310629

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