Ameliorative Potential of (-) Pseudosemiglabrin in Mice with Pilocarpine-Induced Epilepsy: Antioxidant, Anti-Inflammatory, Anti-Apoptotic, and Neurotransmission Modulation

One prevalent neurological disorder is epilepsy. Modulating GABAergic/glutamatergic neurotransmission, Nrf2/HO-1, PI3K/Akt, and TLR-4/NF-B pathways might be a therapeutic strategy for epilepsy. Eight-week-old BALB/c mice were administered 12.5, 25, or 50 mg/kg (-) pseudosemiglabrin orally one hour b...

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Detalles Bibliográficos
Autores principales: Balaha, Mohamed F., Alamer, Ahmed A., Abdel-Kader, Maged S., Alharthy, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341902/
https://www.ncbi.nlm.nih.gov/pubmed/37445950
http://dx.doi.org/10.3390/ijms241310773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341902/
https://www.ncbi.nlm.nih.gov/pubmed/37445950
http://dx.doi.org/10.3390/ijms241310773

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