Cell-Type Specific Regulation of Cholesterogenesis by CYP46A1 Re-Expression in zQ175 HD Mouse Striatum

Cholesterol metabolism dysregulation is associated with several neurological disorders. In Huntington’s disease (HD), several enzymes involved in cholesterol metabolism are downregulated, among which the neuronal cholesterol 24-hydroxylase, CYP46A1, is of particular interest. The restoration of CYP4...

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Detalles Bibliográficos
Autores principales: Pinchaud, Katleen, Masson, Chloé, Dayre, Baptiste, Mounier, Coline, Gilles, Jean-François, Vanhoutte, Peter, Caboche, Jocelyne, Betuing, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341918/
https://www.ncbi.nlm.nih.gov/pubmed/37446179
http://dx.doi.org/10.3390/ijms241311001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341918/
https://www.ncbi.nlm.nih.gov/pubmed/37446179
http://dx.doi.org/10.3390/ijms241311001

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