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Cell-Type Specific Regulation of Cholesterogenesis by CYP46A1 Re-Expression in zQ175 HD Mouse Striatum
Cholesterol metabolism dysregulation is associated with several neurological disorders. In Huntington’s disease (HD), several enzymes involved in cholesterol metabolism are downregulated, among which the neuronal cholesterol 24-hydroxylase, CYP46A1, is of particular interest. The restoration of CYP4...
Autores principales: | Pinchaud, Katleen, Masson, Chloé, Dayre, Baptiste, Mounier, Coline, Gilles, Jean-François, Vanhoutte, Peter, Caboche, Jocelyne, Betuing, Sandrine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341918/ https://www.ncbi.nlm.nih.gov/pubmed/37446179 http://dx.doi.org/10.3390/ijms241311001 |
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