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Activation/Inhibition of Cholinesterases by Excess Substrate: Interpretation of the Phenomenological b Factor in Steady-State Rate Equation
Cholinesterases (ChEs) display a non-michaelian behavior with positively charged substrates. In the steady-state rate equation, the b factor describes this behavior: if b > 1 there is substrate activation, if b < 1 there is substrate inhibition. The mechanistic significance of the b factor was...
Autores principales: | Mukhametgalieva, Aliya R., Nemtarev, Andrey V., Sykaev, Viktor V., Pashirova, Tatiana N., Masson, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341919/ https://www.ncbi.nlm.nih.gov/pubmed/37445649 http://dx.doi.org/10.3390/ijms241310472 |
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