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Investigation of Molecular Interactions Mechanism of Pembrolizumab and PD-1

Human programmed cell death protein 1 (PD-1) is a checkpoint protein involved in the regulation of immune response. Antibodies are widely used as inhibitors that block the immune checkpoint, preventing strong immune responses. Pembrolizumab is an FDA-approved IgG4 antibody with PD-1 inhibitory abili...

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Detalles Bibliográficos
Autores principales: Wang, Simiao, Khan, Faez Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341962/
https://www.ncbi.nlm.nih.gov/pubmed/37445859
http://dx.doi.org/10.3390/ijms241310684