Cargando…

Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice

Tau protein aggregations are important contributors to the etiology of Alzheimer’s disease (AD). Hydromethylthionine (HMT) is a potent inhibitor of tau aggregation in vitro and in vivo and is being developed as a possible anti-dementia medication. HMT was also shown to affect the cholinergic system...

Descripción completa

Detalles Bibliográficos
Autores principales: Kondak, Constantin, Leith, Michael, Baddeley, Thomas C., Santos, Renato X., Harrington, Charles R., Wischik, Claude M., Riedel, Gernot, Klein, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341988/
https://www.ncbi.nlm.nih.gov/pubmed/37445987
http://dx.doi.org/10.3390/ijms241310810