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Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice
Tau protein aggregations are important contributors to the etiology of Alzheimer’s disease (AD). Hydromethylthionine (HMT) is a potent inhibitor of tau aggregation in vitro and in vivo and is being developed as a possible anti-dementia medication. HMT was also shown to affect the cholinergic system...
Autores principales: | Kondak, Constantin, Leith, Michael, Baddeley, Thomas C., Santos, Renato X., Harrington, Charles R., Wischik, Claude M., Riedel, Gernot, Klein, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10341988/ https://www.ncbi.nlm.nih.gov/pubmed/37445987 http://dx.doi.org/10.3390/ijms241310810 |
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