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Overexpression of Hsp104 by Causing Dissolution of the Prion Seeds Cures the Yeast [PSI(+)] Prion
The yeast Sup35 protein misfolds into the infectious [PSI(+)] prion, which is then propagated by the severing activity of the molecular chaperone, Hsp104. Unlike other yeast prions, this prion is unique in that it is efficiently cured by the overexpression as well as the inactivation of Hsp104. Howe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342028/ https://www.ncbi.nlm.nih.gov/pubmed/37446010 http://dx.doi.org/10.3390/ijms241310833 |