Thymoquinone Ameliorates Carfilzomib-Induced Renal Impairment by Modulating Oxidative Stress Markers, Inflammatory/Apoptotic Mediators, and Augmenting Nrf2 in Rats

Chemotherapy-induced kidney damage is an emerging problem that restricts cancer treatment effectiveness. The proteasome inhibitor carfilzomib (CFZ) is primarily used to treat multiple myeloma and has been associated with severe renal injury in humans. CFZ-induced nephrotoxicity remains an unmet medi...

Descripción completa

Detalles Bibliográficos
Autores principales: Qadri, Marwa M., Alam, Mohammad Firoz, Khired, Zenat A., Alaqi, Reem O., Khardali, Amani A., Alasmari, Moudi M., Alrashah, Ahmad S. S., Muzafar, Hisham M. A., Qahl, Abdullah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342029/
https://www.ncbi.nlm.nih.gov/pubmed/37445797
http://dx.doi.org/10.3390/ijms241310621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342029/
https://www.ncbi.nlm.nih.gov/pubmed/37445797
http://dx.doi.org/10.3390/ijms241310621

Ejemplares similares