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Thymoquinone Ameliorates Carfilzomib-Induced Renal Impairment by Modulating Oxidative Stress Markers, Inflammatory/Apoptotic Mediators, and Augmenting Nrf2 in Rats
Chemotherapy-induced kidney damage is an emerging problem that restricts cancer treatment effectiveness. The proteasome inhibitor carfilzomib (CFZ) is primarily used to treat multiple myeloma and has been associated with severe renal injury in humans. CFZ-induced nephrotoxicity remains an unmet medi...
Autores principales: | Qadri, Marwa M., Alam, Mohammad Firoz, Khired, Zenat A., Alaqi, Reem O., Khardali, Amani A., Alasmari, Moudi M., Alrashah, Ahmad S. S., Muzafar, Hisham M. A., Qahl, Abdullah M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342029/ https://www.ncbi.nlm.nih.gov/pubmed/37445797 http://dx.doi.org/10.3390/ijms241310621 |
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