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Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine Sulfonamides as an Important Scaffold for Anticancer Drug Discovery—In Vitro and In Silico Evaluation

Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides (MM-compounds) are a relatively new class of heterocyclic compounds that exhibit a wide variety of biological actions, including anticancer properties. Here, we used caspase enzyme activity assays, flow cytometry analysis of propidium iodid...

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Detalles Bibliográficos
Autores principales: Kciuk, Mateusz, Marciniak, Beata, Celik, Ismail, Zerroug, Enfale, Dubey, Amit, Sundaraj, Rajamanikandan, Mujwar, Somdutt, Bukowski, Karol, Mojzych, Mariusz, Kontek, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342037/
https://www.ncbi.nlm.nih.gov/pubmed/37446136
http://dx.doi.org/10.3390/ijms241310959