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Opioids Alleviate Oxidative Stress via the Nrf2/HO-1 Pathway in LPS-Stimulated Microglia

Opioids are known to have antioxidant effects and to modulate microglial function under certain conditions. It has been previously shown that opioid ligands can effectively inhibit the release of proinflammatory cytokines when stimulated with lipopolysaccharide (LPS) and convert microglia to an anti...

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Detalles Bibliográficos
Autores principales: Shivling Mali, Akash, Honc, Ondrej, Hejnova, Lucie, Novotny, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342087/
https://www.ncbi.nlm.nih.gov/pubmed/37446267
http://dx.doi.org/10.3390/ijms241311089