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Glypican-3 (GPC-3) Structural Analysis and Cargo in Serum Small Extracellular Vesicles of Hepatocellular Carcinoma Patients

Glypican-3 (GPC-3) is a heparin sulfate proteoglycan located extracellularly and anchored to the cell membrane of transformed hepatocytes. GPC-3 is not expressed in normal or cirrhotic liver tissue but is overexpressed in hepatocellular carcinoma (HCC). Because of this, GPC-3 is one of the most impo...

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Detalles Bibliográficos
Autores principales: Mauro, Montalbano, Ugo, Perricone, Walton, Zachary, Ali, Shirafkan, Rastellini, Cristiana, Cicalese, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342088/
https://www.ncbi.nlm.nih.gov/pubmed/37446098
http://dx.doi.org/10.3390/ijms241310922