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Decoding Metabolic Symbiosis between Pancreatic Cancer Cells and Cancer-Associated Fibroblasts Using Cultured Tumor Microenvironment

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor prognosis, largely due to its unique tumor microenvironment (TME) and dense fibrotic stroma. Cancer-associated fibroblasts (CAFs) play a crucial role in promoting tumor growth and metastasis, contributing to the metabo...

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Detalles Bibliográficos
Autores principales: Nihashi, Yuma, Song, Xiaoyu, Yamamoto, Masamichi, Setoyama, Daiki, Kida, Yasuyuki S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342091/
https://www.ncbi.nlm.nih.gov/pubmed/37446193
http://dx.doi.org/10.3390/ijms241311015