Cargando…

Decoding Metabolic Symbiosis between Pancreatic Cancer Cells and Cancer-Associated Fibroblasts Using Cultured Tumor Microenvironment

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor prognosis, largely due to its unique tumor microenvironment (TME) and dense fibrotic stroma. Cancer-associated fibroblasts (CAFs) play a crucial role in promoting tumor growth and metastasis, contributing to the metabo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nihashi, Yuma, Song, Xiaoyu, Yamamoto, Masamichi, Setoyama, Daiki, Kida, Yasuyuki S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342091/ https://www.ncbi.nlm.nih.gov/pubmed/37446193 http://dx.doi.org/10.3390/ijms241311015

Ejemplares similares

The Metabolism Symbiosis Between Pancreatic Cancer and Tumor Microenvironment
por: Li, Ying, et al.
Publicado: (2021)

Rostro-caudal different energy metabolism leading to differences in degeneration in spinal cord injury
por: Ohnishi, Yuichiro, et al.
Publicado: (2021)

Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts
por: Miyazaki, Yoshihiro, et al.
Publicado: (2022)

Adipose‐derived mesenchymal stem cells differentiate into pancreatic cancer‐associated fibroblasts in vitro
por: Miyazaki, Yoshihiro, et al.
Publicado: (2020)

Pancreatic cancer and fibrosis: Targeting metabolic reprogramming and crosstalk of cancer-associated fibroblasts in the tumor microenvironment
por: Li, Xin, et al.
Publicado: (2023)

Targeting and Reprograming Cancer-Associated Fibroblasts and the Tumor Microenvironment in Pancreatic Cancer
por: Sunami, Yoshiaki, et al.
Publicado: (2021)

Heterogeneity of Cancer-Associated Fibroblasts and the Tumor Immune Microenvironment in Pancreatic Cancer
por: Shinkawa, Tomohiko, et al.
Publicado: (2022)

Symbiosis of Electrical and Metabolic Oscillations in Pancreatic β-Cells
por: Marinelli, Isabella, et al.
Publicado: (2021)

Targeting the Metabolic Rewiring in Pancreatic Cancer and Its Tumor Microenvironment
por: Yamamoto, Keisuke, et al.
Publicado: (2022)

Oscillations and Dynamic Symbiosis in Cellular Metabolism in Cancer
por: Amemiya, Takashi, et al.
Publicado: (2022)

Glycolytic System in Axons Supplement Decreased ATP Levels after Axotomy of the Peripheral Nerve
por: Takenaka, Tomofumi, et al.
Publicado: (2023)

STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
por: Lefler, Julia E, et al.
Publicado: (2022)

Decoding the dynamic tumor microenvironment
por: Clauset, Aaron, et al.
Publicado: (2021)

Apoptosis in the Pancreatic Cancer Tumor Microenvironment—The Double-Edged Sword of Cancer-Associated Fibroblasts
por: Pfeifer, Ester, et al.
Publicado: (2021)

Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts
por: Noel, Pawan, et al.
Publicado: (2017)

Therapeutic Potential of Adipose Stem Cell-Derived Conditioned Medium on Scar Contraction Model
por: Imai, Yukiko, et al.
Publicado: (2022)

Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines
por: Gorchs, Laia, et al.
Publicado: (2021)

Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer
por: Kitamura, Fumimasa, et al.
Publicado: (2023)

Cancer-Associated Fibroblasts and Tumor Cells in Pancreatic Cancer Microenvironment and Metastasis: Paracrine Regulators, Reciprocation and Exosomes
por: Sunami, Yoshiaki, et al.
Publicado: (2022)

Matrix remodeling‐associated protein 8 is a marker of a subset of cancer‐associated fibroblasts in pancreatic cancer
por: Ichihara, Ryosuke, et al.
Publicado: (2022)

Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells
por: Takahashi, Kei, et al.
Publicado: (2018)

Cancer-Associated Fibroblast Diversity Shapes Tumor Metabolism in Pancreatic Cancer
por: Peiffer, Raphaël, et al.
Publicado: (2022)

Decoding cultural conflicts
por: Koçak, Özgecan, et al.
Publicado: (2023)

Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironment
por: Zhu, Yifei, et al.
Publicado: (2022)

PANCREATIC CANCER PROLIFERATION IS INDUCED BY GLI2-COL1 SIGNALING IN FIBROBLASTS IN THE TUMOR MICROENVIRONMENT
por: Ross, Madeline, et al.
Publicado: (2022)

Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment
por: Xue, Meilin, et al.
Publicado: (2023)

Crosstalk between Pancreatic Cancer Cells and Cancer-Associated Fibroblasts in the Tumor Microenvironment Mediated by Exosomal MicroRNAs
por: Chu, Xiangyu, et al.
Publicado: (2022)

Cancer-Associated Fibroblasts in the Hypoxic Tumor Microenvironment
por: Kim, Iljin, et al.
Publicado: (2022)

Metabolic constraints for a novel symbiosis
por: Sørensen, Megan E. S., et al.
Publicado: (2016)

The Tumor Microenvironment of Pancreatic Cancer
por: Karamitopoulou, Eva
Publicado: (2020)

The Immune Microenvironment in Pancreatic Cancer
por: Huber, Magdalena, et al.
Publicado: (2020)

OR09-1 Decoding Cancer Immunoediting of Tumor Microenvironment Provides Immunogenomic Marker for Thyroid Cancer Screening
por: Ali, Sophia, et al.
Publicado: (2022)

Good and Bad Stroma in Pancreatic Cancer: Relevance of Functional States of Cancer-Associated Fibroblasts
por: Ando, Ryota, et al.
Publicado: (2022)

GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment
por: Zhou, Quan, et al.
Publicado: (2017)

The heterogeneity of cancer‐associated fibroblast subpopulations: Their origins, biomarkers, and roles in the tumor microenvironment
por: Yamamoto, Yurie, et al.
Publicado: (2022)

Glucose metabolism and tumour microenvironment in pancreatic cancer: A key link in cancer progression
por: Dong, Shi, et al.
Publicado: (2022)

Decoding the Impact of Tumor Microenvironment in Osteosarcoma Progression and Metastasis
por: Nirala, Bikesh K., et al.
Publicado: (2023)

Transcription of Endogenous Retrovirus Group K Members and Their Neighboring Genes in Chicken Skeletal Muscle Myoblasts
por: Takaya, Tomohide, et al.
Publicado: (2021)

Beyond Symbiosis: Cleaner Shrimp Clean Up in Culture
por: Militz, Thane A., et al.
Publicado: (2015)

The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment
por: Monteran, Lea, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lentbv9ha5r1qmuch82kcek4gc